Continuous succinic acid fermentation by Actinobacillus succinogenes in a packed-bed biofilm reactor
نویسندگان
چکیده
منابع مشابه
Succinic acid production on xylose-enriched biorefinery streams by Actinobacillus succinogenes in batch fermentation
BACKGROUND Co-production of chemicals from lignocellulosic biomass alongside fuels holds promise for improving the economic outlook of integrated biorefineries. In current biochemical conversion processes that use thermochemical pretreatment and enzymatic hydrolysis, fractionation of hemicellulose-derived and cellulose-derived sugar streams is possible using hydrothermal or dilute acid pretreat...
متن کاملContinuous succinic acid production by Actinobacillus succinogenes on xylose-enriched hydrolysate
BACKGROUND Bio-manufacturing of high-value chemicals in parallel to renewable biofuels has the potential to dramatically improve the overall economic landscape of integrated lignocellulosic biorefineries. However, this will require the generation of carbohydrate streams from lignocellulose in a form suitable for efficient microbial conversion and downstream processing appropriate to the desired...
متن کاملIsolation of NH₄+-tolerant mutants of Actinobacillus succinogenes for succinic acid production by continuous selection.
Actinobacillus succinogenes, a typical succinic acid producing microorganism, was inhibited seriously by ammonium ion, which hampered industrialization of A. succinogenes with ammonium ion based material as the pH controller. In this study, we have isolated an ammonium ion-tolerant mutant of A. succinogenes by continuous-culture technique in which all environmental factors beside the stress (am...
متن کاملMETABOLIC CAPABILITIES OF Actinobacillus succinogenes FOR SUCCINIC ACID PRODUCTION
Attention has been focused on microbial succinic acid production as an alternative for conventional chemical synthesis that is associated with environmental pollution. A metabolic model for Actinobacillus succinogenes 130Z was developed with a mixture of glucose and xylose as substrate. The metabolic fluxes during succinicate production were determined using flux balance analysis by linear prog...
متن کاملSuccinic acid production with Actinobacillus succinogenes: rate and yield analysis of chemostat and biofilm cultures
BACKGROUND Succinic acid is well established as bio-based platform chemical with production quantities expecting to increase exponentially within the next decade. Actinobacillus succinogenes is by far the most studied wild organism for producing succinic acid and is known for high yield and titre during production on various sugars in batch culture. At low shear conditions continuous fermentati...
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ژورنال
عنوان ژورنال: Biotechnology for Biofuels
سال: 2018
ISSN: 1754-6834
DOI: 10.1186/s13068-018-1143-7